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Phase 2 clinical trial initiated to evaluate SEMA3A mAb as potential treatment for Alport syndromeMilestone payment to Evotec expected upon first dosing of first study participant in early 2026

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Highlights:Initial surface results from North Block across historic mine workings yield high silver valuesOver 1,300 meters drilled to date across the North Block, results pendingSurface data strengthens target areas for drill testing higher grade gold potential at depth.Mineralized shoots and feeder zones could coincide with strong alteration signatures where Ag-Pb-Zn-Sb-As and Au-As-Sb-Bi are present.Road building and preparation work continues in South Block for trenching and extraction.Video Explanation

President Donald Trump said Wednesday he believes Russia's Vladimir Putin wants to end the Ukraine war despite inconclusive talks in Moscow, as US officials prepared for a follow-up meeting with Kyiv's top negotiator.

Liverpool boss Arne Slot conceded his side have lost their fear factor during a miserable run as Sunderland emerged with a 1-1 draw at Anfield on Wednesday.

Enzo Maresca slammed lacklustre Chelsea after their Premier League title challenge suffered a huge setback in a shock 3-1 defeat at lowly Leeds on Wednesday.

Mikel Arteta fears Arsenal's mounting injury problems will hamper their bid to win the Premier League title after Declan Rice and Cristhian Mosquera limped off in Wednesday's 2-0 win against Brentford.

US President Donald Trump said Wednesday he believes Vladimir Putin wants to end the Ukraine war, despite talks between the Russian president and American negotiators ending without a deal.

President Donald Trump announced Wednesday a reset of Joe Biden's fuel-economy standards, arguing it will lower US car prices -- but critics warned it would worsen climate change and leave drivers paying more at the pump.

Mikel Merino maintained his emergence as Arsenal's unlikely goal king as the "unbelievable" makeshift striker inspired the Premier League leaders' 2-0 win against Brentford on Wednesday.

A doctor who supplied "Friends" star Matthew Perry with ketamine in the months before he fatally overdosed, musing to a fellow physician over "how much this moron will pay" for the drug, was jailed in California on Wednesday.

Arsenal edged out Brentford 2-0 to restore their five-point lead at the top of the Premier League on Wednesday as Chelsea slumped to a 3-1 defeat at struggling Leeds.

Chelsea's Premier League title challenge suffered a huge setback as lowly Leeds swept to a shock 3-1 win at Elland Road on Wednesday.

Britain's King Charles III treated German President Frank-Walter Steinmeier to a sumptuous banquet Wednesday, as the pair hailed the countries' deep ties during the first UK state visit by a German head of state in decades.

Harry Kane scored a first-half header as Bayern Munich did just enough to reach the German Cup quarter-finals in a 3-2 win at Union Berlin on Wednesday.

Wall Street stocks shrugged off early weakness Wednesday and finished with solid gains after poor US hiring data boosted expectations that the Federal Reserve will cut interest rates next week.

Arsenal edged out Brentford 2-0 to restore their five-point lead at the top of the Premier League on Wednesday as in-form Aston Villa beat Brighton 4-3 to climb up to third in the table.

Mikel Merino maintained his emergence as Arsenal's unlikely goal king as the makeshift striker inspired the Premier League leaders' 2-0 win against Brentford on Wednesday.

An explosive docuseries about Sean "Diddy" Combs -- produced by his longtime rival 50 Cent -- has been released on Netflix, despite the disgraced music mogul's attempts to block its airing.

Jared Isaacman, US President Donald Trump's two-time appointee to lead NASA, said it was his goal that the United States beat rival China in the race to return humans to the Moon, during a Senate confirmation hearing Wednesday.

Kylian Mbappe scored twice and set up another as Real Madrid beat Athletic Bilbao 3-0 to cut Barcelona's La Liga lead back down to one point on Wednesday.

Biopic "Peter Hujar's Day" on Wednesday topped the nominations for the Spirit Awards, which also saw singer SZA given a nod for her debut film role.

Celtic appointed Frenchman Wilfried Nancy as the new manager of the Scottish champions on Wednesday on a two-and-a-half year contract.

Human rights groups warned Wednesday ahead of the draw for next year's football World Cup that President Donald Trump's hardline immigration policies could overshadow the tournament.

President Donald Trump is poised to roll back his predecessor Joe Biden's tough fuel-economy standards, arguing the move will lower car prices even as critics warn it will leave drivers paying more at the pump and accelerate climate change.

Terence Crawford has been stripped of his WBC super middleweight crown after a financial dispute, with Britain's Hamzah Sheeraz and Frenchman Christian Mbilli to fight for the vacant world title.

Brazilian police said Wednesday they were probing the outbreak of a lethal virus among some of the last Spix's Macaws, one of the world's rarest birds -- made famous as the blue parrot in the 2011 animated film "Rio."

US private-sector hiring data released Wednesday painted a downcast picture of the job market in the world's biggest economy, especially among small businesses.

Russia has blocked access to US-owned online gaming platform Roblox, accusing it of distributing extremist materials and promoting "LGBT propaganda", state media reported Wednesday.

Oval Invincibles will be re-branded as MI London from 2026 after a deal between the Hundred franchise and the owners of Mumbai Indians.

He still mocks his predecessor as "Sleepy Joe" Biden. But it was Donald Trump who seemed to be fighting to stay awake at a cabinet meeting.

The Los Angeles Clippers axed veteran point guard Chris Paul on Wednesday, releasing the 12-time All-Star in a shock move that comes with the team struggling near the foot of the NBA standings.