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The US opioid crisis has claimed more than 500,000 lives in the last 20 years. It has also spawned one of the most complex legal campaigns in the country's history.

Russia, as expected, vetoed a UN Security Council resolution on Friday that "deplores in the strongest terms" the country's "aggression" against Ukraine and demanded the immediate withdrawal of its troops.

Inter Milan failed to capitalise on AC Milan's home draw against Udinese on Friday with a goalless draw at Genoa which allowed their local rivals to stay top of Serie A.

Ukrainian forces fought off Russian troops in the capital Kyiv on Friday as the United States, European Union and Britain announced personal sanctions against Russia's President Vladimir Putin.

Southampton pushed Norwich deeper into relegation trouble as the Premier League's bottom club slumped to a 2-0 defeat at St Mary's on Friday.

The United States top health agency on Friday drastically revised its guidelines for masking to stop Covid-19 transmission, a decision that means most Americans won't be advised to wear them in indoor public spaces, including school children.

AC Milan slipped up for the second time in as many weeks on Friday with a 1-1 draw with Udinese which gave their Serie A title rivals a chance to reach them at the summit.

Five Western nations urged Libyans on Friday not to drag the National Oil Corporation into political disputes that could threaten the country's fragile peace.

No Russian entertainers will be permitted to take part in this year's Eurovision Song Contest following Russia's invasion of Ukraine, the European Broadcasting Union said Friday.

Seven-time world champion Lewis Hamilton laid down an early marker ahead of the new Formula One season on Friday when he set the fastest time in pre-season testing in Barcelona.

Facebook's parent company Meta said Friday that Russia will hit its services with restrictions after the social media giant defied authorities' order to stop fact-checkers and content warning labels on its platforms.

Having lived through numerous financial cataclysms since the fall of the Soviet Union, Moscow's residents seemed resigned Friday in the face of Western sanctions over Russia's invasion of Ukraine, knowing they will have to bear the costs.

Reigning world champion and world record holder Christian Coleman seeks his third consecutive 60-meter crown at this weekend's US Indoor Track and Field Championships in Spokane, Washington.

Ukrainian forces fought off Russian troops in the capital Kyiv on Friday as President Volodymyr Zelensky defied calls by his Russian counterpart Vladimir Putin for him to be overthrown.

The UN's emergency relief coordinator called on Friday for "safe, unimpeded access" for aid workers to carry out humanitarian operations in Ukraine, after the Russian invasion.

Sanctions to limit Russia's access to tech components like semiconductors may temporarily hobble its defence industry, but analysts said they risk boomeranging on the West if Russia withholds key raw materials.

Scotland suffered a major setback on the eve of Saturday's Six Nations match at home to France when star back-row Hamish Watson was ruled out after testing positive for Covid-19.

Russia's attack on Ukraine could herald a Cold War revival in Europe with two blocs armed to the teeth pointing nuclear weapons at each other across an iron curtain, politicians and experts say.

Russia's invasion of Ukraine resulted in serious sporting consequences on Friday as UEFA stripped Saint-Petersburg of hosting the Champions League final and Formula One cancelled the Russian Grand Prix.

Seven-time world champion Lewis Hamilton laid down an early marker ahead of the new Formula One season on Friday when he set the fastest time in pre-season testing in Barcelona.

Ukrainian boxer Viktor Postol, a former world champion at 140 pounds, is thinking of his family and the war in his homeland as he prepares for a crucial fight Saturday.

Russia's invasion of Ukraine has placed a question mark over the future of the International Space Station, long a symbol of post Cold War cooperation, where astronauts and cosmonauts proudly live and work side-by-side.

Why have one logo when you can have two?

Liverpool manager Jurgen Klopp is determined to ensure his side are remembered for their achievements and not missed opportunities as he prepares for Sunday's League Cup final against Chelsea.

Russia's drive to seize control of Ukraine quickly has lost momentum amid resistance from Ukrainian fighters on the ground and in the air, a senior US defense official said Friday.

Anett Kontaveit reached her seventh WTA final since August on Friday when she breezed past Jelena Ostapenko 6-1, 6-4 at the Qatar Open.

As Russian troops approach the Ukrainian capital in an all-out offensive, here are five facts about the country that has long been disputed by great empires.

Tyson Fury will have his first bout on home soil in nearly four years when he defends his World Boxing Council (WBC) heavyweight title in an all-British clash against Dillian Whyte at Wembley Stadium on April 23.

Stuart Hogg says Scotland have the firepower to deny France a Grand Slam even though he rates the Six Nations leaders as one of the best teams in world rugby.

Ukrainian authorities warned Friday that radiation levels had increased in the Chernobyl exclusion zone since it was seized by invading Russian troops, however the UN's nuclear watchdog said it currently "posed no danger".

Former rugby union and rugby league star Va'aiga Tuigamala, who died aged 52 on Thursday, was one of "those people who touch you the first time you meet them", said Ireland rugby union coach Andy Farrell.

David Beckham insists patience is key as the former England captain enters his third season as an owner this weekend following a difficult start in Major League Soccer for his Inter Miami franchise.